Synthesis of amides of 5-arylidene-2,4-dioxothiazolidine-3-acetic acid with 1,2,4-triazole system.
نویسندگان
چکیده
In the reaction of 5-arylidene-2,4-dioxothiazolidine-3-acetic acid chloride with 1,2,4-triazole, 1,2,4-triazoline-5-one and 1,2,4-triazoline-5-thione, the new corresponding 5-arylidene-2,4-dioxothiazolidine-3-acetic acid amides (5-16) were obtained. Compounds 6, 14 i 15 were investigated in vitro for their antioxidant activity.
منابع مشابه
Synthesis of amides of 2,4-dioxothiazolidin-5-yl acetic acid with 1,2,4-triazole substituents.
In the reaction of (2,4-dioxothiazolidin-5-yl)acetyl chloride with 1,2,4-triazole, 4-phenyl-1,2,4-triazolin-5-one and 4-phenyl-1,2,4-triazolin-5-thione, the new corresponding amides (2-4) were obtained. For compounds 2 and 4 effects on central nervous system (CNS) of mice were studied.
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ورودعنوان ژورنال:
- Acta poloniae pharmaceutica
دوره 63 1 شماره
صفحات -
تاریخ انتشار 2006